What should I do about the lines around my mouth? Mainly my left side. Deep smile lines and marionettes? (Photo)

Hi, Thanks for sharing your picture and question. You will be benefited by dermal filler or nano fat fill. Nano fat fill lasts long and improves your fines lines as well. Consult a board certified plastic surgeon. Good luck. 

In my opinion, the best treatment for your nasolabial folds and marionette lines is a filler like Restylane Defyne. Microneedling is a great treatment for uneven skin texture, fine (very superficial) lines, and enlarged pores and can give you fresher, healthier and more radiant skin.