What are side effects rates of Botox for those with fibromyalgia and skin allodynia?

No, Botox should not increase pain for these patients. It takes 1-2 weeks for final results with Botox and they resolve in 3-4 months. Best, Dr. Emer

People with fibromyalgia and pain sensitivity likely will experience slightly more pain with their Botox treatment. That said, Botox typically hurts about 1/10 on a pain score, although some people rate it 0 and others rate it up to a 5. You may want to take acetaminophen and/or apply topical anesthetic prior to your treatment to really minimize your discomfort. Another option is just to treat a small area, and see how it goes, and if feeling up to it, go on to treat the rest the same day or a different day. An expert and highly trained injector such as a dermatologist can assess you in person to optimize safety, minimize pain, and give you optimal results & duration with your Botox.

I commonly inject Botox in fibromyalgia patients, mainly following the chronic migraine protocol. They may experience slightly more pain from the needle sticks, but they do not have any additional side effects from the Botox itself.