5 years post Bellafill - do the microspheres move after 5 years?

Question

I had bellafill injected into my temples in 2019 for acne scarring. It’s been 5 years since and I’ve read that belafil lasts 5 years. What I’ve been concerned about is what happens to the PM Microspheres after 5 years? I’ve read they don’t dissolve, so my question is do the microspheres move after 5 years? I’m worried that they will migrate toward my eyes. I dont know if this has ever happened or it is a likely possibility?

Raffy Karamanoukian, MD, FACS · Answer

Bellafill PMMA microparticles are likely permanent within the soft tissue. At the 5 year point, you may consider a followup visit with your injector or our office to determine the status of your PMMA injections. Longterm fillers require longterm maintenance.

Best.
Dr. Karamanoukian
Realself100 Surgeon

Best. 
Dr. Karamanoukian
Realself100 Surgeon

Anna Chacon, MD, FAAD · Answer

Bellafill is a dermal filler that contains polymethyl methacrylate (PMMA) microspheres suspended in a collagen gel. The collagen component is gradually absorbed by the body over time, while the PMMA microspheres remain in place and stimulate the body's own collagen production to maintain volume.

It's important to note that PMMA microspheres are designed to be biocompatible and stable. Here are some key points regarding your concerns:

1. **Longevity and Stability**: The PMMA microspheres in Bellafill are intended to provide a long-lasting effect. While the collagen gel component is absorbed, the microspheres remain and act as a scaffold for new collagen growth. These microspheres are not designed to dissolve or break down.

2. **Migration**: The PMMA microspheres in Bellafill are intended to remain in the location where they were injected. There is a very low risk of migration because the microspheres are embedded in the body’s own collagen matrix, which helps to keep them in place. Instances of migration are rare and usually occur due to improper injection technique or other complications.

3. **Safety Profile**: Bellafill has been used for many years, and its safety profile is well-documented. There have been no widespread reports of PMMA microspheres migrating toward the eyes or other unintended areas when injected properly.

4. **Consultation**: If you have specific concerns about the long-term effects of Bellafill or are experiencing any unusual symptoms, it's best to consult with a board-certified dermatologist or plastic surgeon who has experience with Bellafill. They can provide personalized advice and, if necessary, perform imaging studies to ensure that the filler is still in the correct location.

In summary, while it's understandable to have concerns about the long-term presence of PMMA microspheres, the design and usage of Bellafill aim to minimize risks such as migration. However, if you have any symptoms or worries, seeking professional medical advice is always the best course of action.

Michael I. Echavez, MD · Answer

The Bellafill microspheres do not go away and should not move after 5 years.  The reason that it is stated that Bellafill lasts 5 years is that the studies the manufacturer performed only followed the results to 5 years and not afterwards.  The results should not alter after 5 years, but aging still will occur, so it is possible that a change in appearance could happen with time.

5 years post Bellafill - do the microspheres move after 5 years?

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