How and should I treat corner mouth "dimples" or smile lines with fillers at 35 yrs old? (photos)

A combination approach would give the most improvement. Deep wrinkles and smile lines can be improved with a combination of Botox and/or fillers for the lines themselves and to build anatomical support with Sculptra for collagen building. Ultherapy is a great skin tightening device, but works best in combination with other treatments like J Plasma, RF treatments, lasers, microneedling/PRP, salt facials, Cosmelan for skin tightening and improve skin tone. I recommend getting a formal evaluation with an expert. Best, Dr. Emer

In general dermal filler is the first consideration of most physicians to help what you are describing. Which type, how much, and where placed has to be determined by an in person evaluation. Most people seeing an experienced injector get good results for shadows, and moderate results for diminishing lines. Other options are available for general facial rejuvenation, short of surgery - such as NovaThreads, a non-surgical treatment for lifting, Ulthera (ultrasound tightening), micro needling, fractional resurfacing with lasers, and others. However, which of these options may be best for you has to be determined in a clinical setting.

Filler can be placed in that area to soften the appearance . There are many brands available, restylane has some newer products that work with areas that require more facial movements