Thank you for your question about the fat lump and fullness beside your mouth. Determining the cause of a lump or fullness in the cheek area can be challenging without a physical examination. However, I can provide some insights into the potential causes you mentioned: Migrated Cheek Filler: Dermal fillers can sometimes migrate from their original injection site. If you have had fillers in your cheeks, it's possible that some of the product could have moved to a lower area. This can create lumps or uneven fullness. Sculptra: Sculptra works by stimulating collagen production over time, which can lead to gradual volume increase. If you have had Sculptra injections, the fullness could be due to the collagen growth stimulated by the treatment. However, lumps are less common with Sculptra compared to hyaluronic acid fillers. Buccal Fat: Buccal fat is the natural fat pad located in the lower cheek area. Some individuals naturally have more prominent buccal fat, which can create a fuller appearance around the mouth and jawline. This is not related to any injectable treatments. To accurately diagnose the cause of the lump and fullness, I recommend scheduling an appointment with a board-certified dermatologist or plastic surgeon. They can perform a thorough examination and may use imaging techniques, such as ultrasound, to determine the nature of the lump. This will help in devising an appropriate treatment plan. Best regards,