Hi! I been getting Botox for over 10 years and my body seems to be resistant…I’ve tried Jeuveau, Daxxify, Dysport, etc. Can someone please provide insight on the best Botox alternative? Which alternative is the “best” and most effective? So sick of wasting my $$$. Please help! Thank you!
April 20, 2025
Answer: Consider Xeomin When Other Neuromodulators No Longer Work Resistance to Botox does happen, despite claims to the contrary. People who have received treatment with Botox, as well as others, such as Jeuveau and Dysport, in higher dose ranges, or too frequently or have had touch up treatments too soon after the primary treatment (such as one to two weeks after the initial treatment), are more likely to develop resistance. In such cases, the resistance stems from essentially being vaccinated to the neuromodulator by the too frequent or too soon touch up treatments. It can also come as a result of antibodies to the complexing proteins that are attached to the active molecule. In the latter case, Xeomin can be tried, as the manufacturer has eliminated the complexing proteins that may be responsible for initiating the immune reaction responsible for the loss of product effectiveness. I have had success with Xeomin in patients who have come to me after having been too frequently treated with the other neuromodulators on the market. You would be wise to make sure to consult with an experienced, board certified cosmetic dermatologist. Hope this helps and best of luck.
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April 20, 2025
Answer: Consider Xeomin When Other Neuromodulators No Longer Work Resistance to Botox does happen, despite claims to the contrary. People who have received treatment with Botox, as well as others, such as Jeuveau and Dysport, in higher dose ranges, or too frequently or have had touch up treatments too soon after the primary treatment (such as one to two weeks after the initial treatment), are more likely to develop resistance. In such cases, the resistance stems from essentially being vaccinated to the neuromodulator by the too frequent or too soon touch up treatments. It can also come as a result of antibodies to the complexing proteins that are attached to the active molecule. In the latter case, Xeomin can be tried, as the manufacturer has eliminated the complexing proteins that may be responsible for initiating the immune reaction responsible for the loss of product effectiveness. I have had success with Xeomin in patients who have come to me after having been too frequently treated with the other neuromodulators on the market. You would be wise to make sure to consult with an experienced, board certified cosmetic dermatologist. Hope this helps and best of luck.
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April 18, 2025
Answer: It is possible that you neutralizing antibodies to botulinum toxin A but unlikely. It is more likely that the crummy treatment pattern you have been getting is no longer getting the job done. Generally we do not test for botulinum toxin antibodies. That is really only done for research studies. What you should know is that if you actually do have neutralizing antibodies to one botulinum toxin A, likely it will effect all of the botulinum toxin A products including Daxxify Jeuveau, etc, Study my patented Microdroplet Lift® . Stay away from bad fillers like Radiesse, Sculptra, and grafted fat. At your age, it is improbable that you need surgery but there is no substitute for an actual in person consultation.
Helpful
April 18, 2025
Answer: It is possible that you neutralizing antibodies to botulinum toxin A but unlikely. It is more likely that the crummy treatment pattern you have been getting is no longer getting the job done. Generally we do not test for botulinum toxin antibodies. That is really only done for research studies. What you should know is that if you actually do have neutralizing antibodies to one botulinum toxin A, likely it will effect all of the botulinum toxin A products including Daxxify Jeuveau, etc, Study my patented Microdroplet Lift® . Stay away from bad fillers like Radiesse, Sculptra, and grafted fat. At your age, it is improbable that you need surgery but there is no substitute for an actual in person consultation.
Helpful