Hello, and thank you for your question about abnormal fat accumulation beneath the glutes and inner thighs. I appreciate the history and pictures you provided. Based on your description and photos, you have excess fat and skin in the inner thighs that extend from the groin to the inner knee. This is medically referred to as cutis pleonasmus (excess skin) and dermatochalasis (loose skin). The best long-term solution is to lose as much weight as possible since overall fat distribution and skin laxity will significantly improve with weight loss. If weight loss has been challenging, you may consider vertical gastric sleeve surgery or FDA-approved weight loss medications like GLP-1 receptor agonists (Ozempic, Mounjaro, Tirzepatide, and Zepbound). While these treatments will not completely eliminate your concerns, they will improve your overall body contour and reduce the amount of excess fat and bulk in the thighs. If weight loss alone does not fully address your concerns, there are two primary surgical options to consider: VASER liposuction and a thigh lift (thigh reduction surgery). VASER liposuction removes excess fat from the inner, anterior (front), and outer lateral thighs, effectively reducing the overall thigh circumference. The procedure takes about 3 to 4 hours under general anesthesia, and while it will significantly reduce fat volume, it will not address excess skin. This means that while your thighs will be slimmer, you may be left with sagging or wrinkled skin. Compression garments must be worn for at least 6 to 8 weeks post-op to promote skin contraction. If you have a sitting job, you can expect to return to work within 7–10 days after liposuction. For patients with significant skin laxity, a thigh lift is the better option. This procedure combines liposuction with skin excision, using an incision that extends from the groin to the knee to ensure optimal skin tightening. A thigh lift is performed under general anesthesia and takes about 4 hours to complete. Drains typically remain in place for 2–3 weeks to prevent fluid buildup, and a compression garment must be worn for 6–8 weeks to optimize healing. Recovery time depends on your occupation; if you have a sitting job, you can return to work within 2–3 weeks, while a standing job may require 3–4 weeks of recovery. Regardless of the procedure chosen, a compression garment is essential for 6–8 weeks postoperatively to promote healing and improve contouring. If you are considering surgery, I strongly recommend consulting with an experienced, board-certified plastic surgeon who has performed at least 100 thigh lifts and can provide a detailed portfolio of before-and-after results. I hope this information helps answer your question, and I wish you the best of luck with your transformation. Sincerely, Dr. Katzen