Is Kybella permanent?

Doctor Answers 65

How Long Kybella Lasts

Kybella does permanently eliminate fat cells after a series of treatments; however please note that new fat cells may emerge with weight gain.  For best results, it is important to complete the series of injections recommended by the doctor and maintain a healthy lifestyle and weight.  I hope this helps!

Pittsburgh Facial Plastic Surgeon
4.9 out of 5 stars 47 reviews

Permanent Fat Reduction with Kybella(R)

Yes, fat reduction resulting from Kybella(R) treatment is permanent.  Kybella(R) is made of deoxycholic acid, a substance that is naturally found in your body, although Kybella(R) is manufactured, not human or animal-derived.  Kybella(R) treatment results in permanent destruction of fat in the approved under-chin treatment area.

Tina B. West, MD
Washington Dermatologic Surgeon
5.0 out of 5 stars 21 reviews

Kyeblla is Permanent To Submetntal Fat Reducation

The results of Kybella is permanent, but requires a number of treatments to get the ultimate result.  Please find a physician with experience.  Best, Dr. Emer.

Jason Emer, MD
Los Angeles Dermatologic Surgeon
4.8 out of 5 stars 196 reviews

Kybella: Permanent or Temporary?

Thanks for your question! Concerning whether Kybella is permanent or temporary, it is actually permanent. Kybella triggers fat cells to initiate cell death. The remains of the dead cells are then flushed out of your body with the help of your immune system. These fat cells will no longer be able to function or store extra calories. They will also not grow back.

However, you also need to know that although Kybella can PERMANENTLY eradicate your fat cells under the chin after a specific number of treatments especially planned for you, new fat cells could develop together with weight gain.

If you are to undergo Kybella treatment, you need to also be prepared not only consistently finish the treatment plan set for you, but also maintain a healthy weight as well as lifestyle. Consult your surgeon for more tips on how to maintain a Kybella treated under chin.

Best of luck!

Robert W. Sheffield, MD
Santa Barbara Plastic Surgeon
4.9 out of 5 stars 29 reviews

Is Kybella Permanent

Thanks for your question. The effects of Kybella are thought to be permanent. The Kybella directs the fat cells to undergo cell death and the remains of the fat cells are then cleared by your body's immune system. Once those cells are gone, they can no longer contribute to storing excess calories so while those cells affected by Kybella will never grow back, those fat cells not touched by Kybella may grow in size if significant weight is put on.

Alexander Ereso, MD
Mountain View Plastic Surgeon
5.0 out of 5 stars 9 reviews


Thank you for your question.  Kybella safely disrupts submental fat cells and dissolves them permanently by destroying the membrane of a fat cell. Any remaining pieces of disrupted fat cells are naturally absorbed by the body using normal metabolic pathways.  I recommend seeking an experienced physician for a consultation.  Best of luck to you.

P. Alexander Ataii, MD
San Diego Physician
5.0 out of 5 stars 6 reviews

Kybella Results

Thank you for your question!  Yes, Kybella permanently reduces the number of fat cells under the chin after a series of injections.  Kybella is a synthetic deoxycholic acid which is injected into the submental neck fat as a 10-15 minute in-office procedure. Over a period of a few weeks, the Kybella destroys the fat cells resulting in an improved neck contour.  While the treated cells are gone forever, it is important to maintain a healthy weight to continue to see good results after treatment. I would suggest consulting with a board-certified facial plastic surgeon or plastic surgeon, to determine if you are a candidate for Kybella, Coolsculpting, or liposuction. 

Best regards,

Dr. Mehta

Umang Mehta, MD
Bay Area Facial Plastic Surgeon
4.7 out of 5 stars 49 reviews

Kybella Results

Thank you for your question. Kybella destroys the fat cells so they are permanently gone. However, if you gain weight the left over fat cells if full series of treatment is not completed (for best results 4-6 treatments is needed) then the remaining fat cells can expand as you gain weight. 

Wish you all the best,

Dr. Mentz 

Henry Mentz, MD, FACS
Houston Plastic Surgeon
4.4 out of 5 stars 35 reviews

Yes Kybella treatment is permanent.

Kybella treatment is permanent because its active ingredient deoxycholic acid breaks down the fat cells in the treated area which is then resorbed by the body.

Peter Chien, MD, PhD
New York Dermatologist
4.5 out of 5 stars 2 reviews

Kybella results are permanent

Once fat is destroyed, it cannot return.  So fat dissolved by Kybella, frozen by coolsculpting cool mini or removed by liposuction, is gone.  The degree of permanent improvement depends on the percentage the fat is reduced.  Because any fat cells that remain can increase in size.  To get the desired results, most patients require several kybella treatments at 6 week or more intervals.  Once achieved, the results are permanent.

I hope this answer helps. Best wishes.

Heidi A. Waldorf, MD
New York Dermatologist
5.0 out of 5 stars 11 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.