What filler will last the longest for Hand Rejuvenation?

Fat transfer, if done adequately
in the hands, will overcorrect by 50-75%.
Non-surgical treatment for hand rejuvenation can be done by using Radiesse.
Both are effective long term and will restore
volume.

If as an older person, one notices some atrophy of the top of the hand, with the tendons and intervals between them getting more noticeable, then the use of fat to restore volume is the most long-lasting option, since fat that is successfully transferred is now living and part of the tissues of the hand. Stem cells in the transferred fat may also contribute to an improved quality of skin and improved appearance. The procedure is done with local anesthetic and fat is harvested from an available donor site, such as the love handles or lower abdomen.  The hands would have to be kept fairly immobile for several days to allow the fat to take.