Lips swelling after facial numbing cream - Is it the numbing cream?

Hi, I’ve had three treatments if Vivace an each time I had a reaction of significant swelling of my lips and irritation in my mouth. Is it the numbing cream? After first treatment, the reaction took 5 days to manifest and 3 days after the second treatment. So I didn’t attribute the reaction to the numbing cream at that time and thought it was from a new toothpaste I had stated. After the last treatment, the reaction started that night.