Sculptra is a biostimulatory filler that works by stimulating collagen production over time, which can help improve skin texture and volume. It is often used to treat facial volume loss and can be beneficial for certain types of acne scars, particularly those that are depressed or cause uneven texture due to volume loss. Given your history of trying various treatments like subcision, lasers, and microneedling without much success, Sculptra might be worth considering as part of a comprehensive treatment plan. It’s important to note that results with Sculptra are gradual and typically require a series of treatments over a few months to achieve the desired outcome. However, the effectiveness of Sculptra for acne scars can vary depending on the type and severity of the scars, as well as individual skin characteristics. Consulting with a dermatologist experienced in treating acne scars with biostimulators will be crucial to determine if Sculptra is appropriate for your specific case and to discuss a personalized treatment plan. They may also recommend combining Sculptra with other treatments to optimize results.