Will Juvederm Cause Scars on Keloid-prone Skin?

I want to get Juvederm for under eye puffiness, and nasolabial folds. My only concern is that I have keloid prone skin. Will the injections leave tiny scars throughout my face?

Doctor Answers 9

Keloids have a mind of their own

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Although keloids are less common around the eye area, they have a mind of their own, so to speak. Any trauma to the skin can incite a keloid scar to form. Consider injecting through the mouth into your eyelid area, but know that the mouth is a dirty environment and the material can theoretically, at least, get infected. The nasolabial fold injections are done within the skin layers and cannot effectively be administered through the mouth. Good luck!

Juvederm injections not advisable for keloid-prone skin

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Keloid scars are caused by a proliferative deposition of collagen into a wound that may or may not plateau. The incipient cause by as simple as a scratch on the skin to a more invasive surgical scar. Keloids commonly occur from ear piercing, which is analagous to needle injections during Juvederm treatment.

I would not advocate any elective procedure that involves injection, surgical incision, or surgical excision for patients with keloid scars unless absolutely necessary.

Raffy Karamanoukian, MD, FACS
Los Angeles Plastic Surgeon
4.8 out of 5 stars 95 reviews

Keloid skin and filler injections

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It is unlikely to develop keloids from small needle injections, however, any skin trauma may induce keloid formation, so I would be hesitant to do so.

Steven Wallach, MD
New York Plastic Surgeon
4.2 out of 5 stars 30 reviews

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No guarantee that keloids won't form after Juvederm

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Many patients who have keloids are able to have fillers, including Juvederm without keloids developing at the insertion site of the needle or the area in which the filler resides. No one can guarantee that you won’t develop a keloid from the Juvederm, provided that it is inserted with a small needle and good technique without any additional surgical procedure being done at the same time (such as subcision which is a procedure that entails breaking up the collagen below the are to be filled by using a needle tip).

Ronald Shelton, MD
Manhattan Dermatologic Surgeon
4.9 out of 5 stars 39 reviews

Filler injections and keloids

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I agree that the risk of keloid development from filler injections even in keloid-prone skin is very low, but ultimately you would need to decide if it is worth the risk. Injections done through the inside of the mouth can give equally nice results. You may need to do a bit of searching for an injector experienced with this technique.

Good luck.

Bryan K. Chen, MD
San Diego Dermatologist

Has Anyone Seen or Heard of a Facial Keloid After Juvederm Injections..or Any Filler for that Matter

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Hi Fernanda,

Even in patients who are known to keloid, it is extremely rare to form keloids on the face (other than the ear). I have not seen or heard of a patient who developed keloids after facial injection of fillers. Discuss your concerns thoroughly with your physician prior to your treatment. Good luck and be well.

Dr. P

Michael A. Persky, MD
Encino Facial Plastic Surgeon
4.8 out of 5 stars 39 reviews

Probably safe, but no guarantees can be made

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The central "T" of the face including the eyes and nose is for some unknown reason generally protected from keloid formation. This plus the fact that Juvederm is injected through a very tiny needle should make this a safe process. Unfortunately, the only way to be absolutely safe is to not do it through the skin. Make sure if you proceed that your injector has experience with going through the mouth.

Keloids are unpredictable

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Keloids are very unpredictable and any trauma to the skin can potentially lead to keloid formation. The best predictor is previous keloids. With facial injections, one step that can be used is to perform the injections from inside the mouth. With this method, there is no external skin puncture and this may reduce the incidence of keloid formation. Good luck.

Keloids on the face are MUCH less common than on the body.

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To Fernanda83,

Hi! Fillers are injected with a tiny needle which makes a tiny (invisible) wound. Theoretically, any punture wound can become a keloid. But I have not seen this, and we treat dark skinned people, and people who have keloids on their body (for example, C section scar). So although there are no guarantees, I would say your risk is very low.

By the way, you should not use Juvederm in the undereyes. Restylane is safer and more forgiving there. For the nasolabial folds, I use Restylane if they are superficial, and Juvederm if they are deeper. Mostly Juvederm.

George J. Beraka, MD (retired)
Manhattan Plastic Surgeon

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.