Juvederm Side Effects

I'm thinking of having Juvederm for deep wrinkles between brows. Are there any side effects?

Doctor Answers 28

Juvederm is risky between the eyes

There have been many people successfully treated with Juvederm or Restylane between the eyes; That being said; this is a particularly risky area with reports of skin necrosis of the forehead and even blindness because some of the product inadvertently entered an artery that communicates with blood flow to the eye; It is far better to treat this area with Botox to relax the muscles that are making the frown lines. If you keep your Botox up without letting it completely wear off between sessions (injections every 3-4 months) eventually the skin starts to recover and the lines get better. Other procedures such as some laser treatments in conjunction with Botox will also help improve those lines.  Occasionally fillers are needed for the best result and in that case, please go to only an expert and hopefully they use a blunt tip canula which makes injections safer.
I hope this helps!
Dr. Quenby Erickson

Botox is primary treatment of "11 lines" but filler can be beneficial

Botox to weaken the corrugator muscles will give you the most benefit with regard to reducing your "11s." If you still have a residual wrinkle this is likely imprinted on the skin and can be improved with Restylane or Juvederm. This can be difficult to treat without causing a bumpy contour or revealing the filler product so consult with an experienced injector before pursuing filler in the area between the brows.

Stephen Weber MD, FACS

Juvederm fills indention, with minimum side effects!

The first line of defense for wrinkles between the brows is typically Botox, this stops the muscles that cause the wrinkle from contracting.If your wrinkles are deeper and present even when your muscles are at rest, then Juvederm would be the best answer (we call these static wrinkles). The Juvederm fills in the indention to smooth the area out. Juvederm really is a very safe product. Most of the issues associated with Juvederm revolve around injection site issues, and many are short lived. Most patients experience swelling and some degree of redness and discomfort at the injection site.Bleeding and bruising can also occur, but are much less likely if you avoid blood thinning medicines for 2 weeks prior to the injection (Aspirin, Motrin, Aleve, Ibuprofen). Typically injected areas are a little firm at first, but this usually softens over time. Itching or discomfort at the site also occur in rare instances. Major complications or allergic reactions to Juvederm are also extremely rare. These kinds of side effects can happen with any injectable fillers and are not more common with Juvederm than with any other filler.

Juvederm, Are There Any Possible Side Effects?

Hi Cons,

As with any medical procedure there are risks and complications involved in the injection of Juvederm between the brows.

I have seen and heard of one patient who has an immediate allergic reaction to hyaluronic acid products (both Juvederm and Restylane). There have been reported cases of skin necrosis (dead skin) from injecting the product directly into a blood vessel. Along the same lines, there have been reported cases of blindness from injecting into the orbit.

Best to choose your injecting physician most carefully. Good luck and be well.

Dr. P

Michael A. Persky, MD
Encino Facial Plastic Surgeon
4.8 out of 5 stars 34 reviews

Juvederm Side Effects

The best treatment for between the brows is Botox. Botox stops the muscles that cause wrinkles. You can place filler between the brow region but one needs to be very careful due to complications from injecting into a blood vessel which can lead to an ulceration and rarely has been associated with blindness.

Hardik Soni, MD
Summit Emergency Medicine Physician
5.0 out of 5 stars 17 reviews

In between brows, how to improve deep lines.

Hi, great question. If you are looking to improve the area between your brows, I would suggest trying botox first or using it in addition to fillers. These lines in between the brows develop because of the strong muscles in this area, fillers can help the wrinkles but they will quickly reform with regular facial expressions. If you maintain with botox through the year every 3-4 month you can help to reverse wrinkles and prevent them from forming.

- Dr. P

Kaleroy Papantoniou, MD, FAAD
Long Island Dermatologic Surgeon
5.0 out of 5 stars 23 reviews

Possible Side Effects From Juvederm

You may experience temporary swelling, mild discomfort/tenderness of the injected area/s, redness, lumps, mild bruising, and possible itching. Most side effects are mild or moderate in nature, and are short lasting.


#JuvedermSideEffects #JuvedermTemporaryEffects

Jed H. Horowitz, MD, FACS
Orange County Plastic Surgeon
5.0 out of 5 stars 93 reviews

Juvederm side effects

Consider injectables implants and not medicines and you will approach them differently when considering getting filler.  Ask your injector if they know the side effects, including how to handle complications such as necrosis, loss of vision, in addition to bruising, swelling, and erythema.  

Sean Paul, MD
Austin Oculoplastic Surgeon
5.0 out of 5 stars 8 reviews

Juvederm for 11s

Thanks for this question.

The 11s ( medial brow ) are best treated with Botox. This is easily preformed with very minimal complications especially if you don't have any eyelid or eyebrow issues.

Juvederm can be injected, by an experienced person in small amounts in the 11s. This is a highly expert indication, as there are reports of loosing some skin in that area and thus getting a scar.

I really recommend trying the Botox first.


Side Effects of Haluronic Acid Fillers

Fillers in the glabella can have rare but serious complications such as tissue loss and embolization.  It is very important to be aware of these potential complications.  Make sure your fillers is being done by a Board Certified Plastic Surgeon or Dermatologist with a proven record.  Many physician extenders are now doing fillers and oftentimes the procedure is being done outside of a physician office.

John Burns, MD
Dallas Plastic Surgeon
4.6 out of 5 stars 31 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.