If the CO2 laser will include the nose or central face, I generally prefer completing the rhinoplasty first. Rhinoplasty changes the nasal skin envelope and creates prolonged swelling; treating that skin with an ablative laser shortly beforehand can add inflammation, pigment change, infection risk, and delayed healing. After rhinoplasty, wait until the incisions are fully healed and most swelling has settled—commonly at least 3 to 6 months, and often 6 to 12 months for aggressive laser treatment directly over the nose. If the laser is limited to areas away from the nose, it may be possible sooner, but the rhinoplasty surgeon and laser physician should coordinate the timing. If CO2 resurfacing has already been done, allow complete re-epithelialization and resolution of redness and sensitivity before surgery; for a fully ablative treatment, this is often several months. The exact interval depends on laser depth, your skin type, history of pigment change or abnormal scarring, medications, and whether an open rhinoplasty is planned. Avoid scheduling the procedures close together and obtain an in-person skin and nasal examination before setting dates.