In What Cases is There a Risk of Scarring from Sclerotherapy?

The potential adverse side effects from sclerotherapy treatment to lower extremity veins include, but are not limited to, discoloration, ulceration and/or scarring at the site of the injections. That being said, these adverse side effects are quite rare. It is possible to develop redness and mild bruising at the treated sites, both of which typically resolve within a few weeks. Sclerotherapy is still considered first line treatment for most lower extremity veins. 

Sclerotherapy is a Safe Procedure with Minimal Risk of Scarring. However, if the sclerosant solution is mistakenly injected outside the intended blood vessel, there may be a blister and crust formation, which may result in a scar. This is not a common occurrence and may be avoided with proper technique. Patients with connective tissue disease (lupus and antiphospholipid antibody syndrome) may be at greater risk of ulceration and scarring if extravasation occurs.