Immune to Botox? Is it possible that I have antibodies that would prevent me from getting results from Botox?

Rare, but not unreasonable....however, from the wording of your question, the botulinum toxin you received never worked for you. I have had a few patients with the same issue....Recently I have treated these patients with a higher concentration of the medication and therefore a smaller volume which allows less migration of the drug and therefore has been more effective. I also think this limits the amount of effective drug needed and lowers the risk of immunity in the future...only theoretical though. 

There is also recent information, and I am awaiting scientific data, to show that vitamin supplements (Zinc) may increase the effectiveness of Botox injections. We'll see....

Hope this helps!

Dr. C

johnconnorsmd.com

There is about at 1 in 10,000 chance of developing antibodies to Botox.   I have seen two patients in my practice with this problem.  If you are concerned, your blood can be tested for the antibodies.  Also, there are other botulinum toxins, such as Myobloc, which can be used effectively in patients with immunity.  Good luck.

It is possible, although unlikely, that you have antibodies to the Botox being injected into your body. If this is the case, Botox will not have the same effect on your body as it does in other patients. You will effectively be immune to the treatment. One option is to try a different strain of botulinum toxin, like Dysport, to see if this is any better in controlling the unwanted muscle movement.