Can Hyaluronidase be used dissolve unwanted, 6 year old Biogel filler?

Question

I had biogel 6 years ago and want it out. I looked into this site for guidance and found only wold have considered open surgery solutions. Then I was told about this injection (Hyaluronidase) that is suppose to dissolve the granulomas. Is this a fact or a myth?

William Groff, DO · Answer

Hyaluronidase is a safe and effective treatment, when used in the right hands, to dissolve unwanted Hyaluronic Acid-based fillers. It depends on what material is in the biogel that was injected.  If it contained only hyaluronic acid, hyaluronidase would be an effective treatment to have. There are many cases where biogel has other components, such as PMMA, that would not respond to hyaluronidase. I suggest scheduling a consultation, and having all future injections with, a board-certified cosmetic dermatologist who is an expert in facial rejuvenation. In my practice, we have over 45 lasers that we use in combination with other treatment modalities, such as Botox, Jeuveau, and dermal fillers, to customize treatments unique to the needs and goals of each of our patients.

Raffy Karamanoukian, MD, FACS · Answer

Longterm filler problems include migration, edema, and nodularity. Filler migration and permanence is a very common problem because there are many different types of HA fillers on the market and each is specified for a specific part of the face. Use of highly cohesive fillers on thin skin may cause swelling and nodularity. If patients have filler migration or nodules, we recommend a combination approach of filler reversal with enzymes Hylenex and Hyaluronidase in different strengths to dissolve the filler. We may also need to add Kenalog to the mix in order to reduce fibrous tissue. If the filler does not dissolve, it either means the filler is not HA material or we need more enzyme. The HA reversal can be combined with other lasers and skin treatments at the same time, and it usually (usually) does not affect adjacent tissue.

Best,
Dr. Karamanoukian
Realself100 Surgeon

Best, 
Dr. Karamanoukian
Realself100 Surgeon

F. Victor Rueckl, MD (in memoriam) · Answer

If the "biogel" you had is a hyaluronic acid filler, then yes, hyaluronidase will help dissolve it. Please remember to find an expert as getting rid of filler is just as much as art as putting it in!"This answer has been solicited without seeing this patient and 
cannot be held as true medical advice, but only opinion. Seek in-person 
treatment with a trained medical professional for appropriate care."

Can Hyaluronidase be used dissolve unwanted, 6 year old Biogel filler?

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Answers (3)

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WE SEND PRETTY
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