Do the juvederm vycross fillers ACTUALLY respond to hyaluronidase?

Hyaluronidase will dissolve vycross fillers, however, sometimes it takes multiple sessions to completely remove.  

As the HA filler you have used is longer-lasting it can also more challenging to dissolve at times. You may find that you will need more than one session or higher amounts of hyalurodinase to completely dissolve the filler. I hope that is useful and best of luck!

Hello L2U.  The same technology (Vycross) that helps these products last longer is the same technology that makes them harder to dissolve.  This means that multiple visits are required in most cases to dissolve the filler.  Best of luck.

The Juvederm Vycross range of fillers have excellent longevity due to the high level of cross-linkage. However, this does present an issue with dissolving the filler if complications occur. 
In short, these fillers do respond to Hyaluronidase. However, due to the high degree of cross-linkage, it is likely to take more than one session to completely dissolve the product. 

Thanks for your question.  Hyaluronidase will dissolve HA products but as they have more cross linking, they may take more product to dissolve and more treatments.