Will Hyalurindase Help with Removing Silicone from Lips?

I have successfully removed silicone in the lips from many women with enormous success. The treatment is usually outpatient and can restore normal contours to the lips. Raffy Karamanoukian Los Angeles

Hyaluronidase will desolve hyaluronic acid fillers. (i.e.: Restylane and Juvederm).  Silicone is not hyaluronic acid based and therefore it won't work for that. Silicone is thought to be a permanent filler that does not have a chemical to dissolve it.  Best to see a board certified plastic surgeon or otolaryngologist, (ENT).  They will guide you through the process that might include excision.

Hyaluronidase is an enzyme that degrades hyaluronic acid which is contained in Restylane and Juvederm. Injectable silicone does not contain this acid so it will not be affected by hyaluronidase.

Although I have seen some good long-term results from silicone injections into lips, I think that for most people permanent injectable materials in the lips will cause problems at some point. Hyaluronidase is an enzyme that breaks down hyaluronic acid, the building block for Restylane, Juvederm, and Perlane. Kenalog is a steroid similar to cortisone, so it helps with inflammation and swelling but also won't affect the silicone. It may require surgical removal if it continues to be a problem. Wish I had better news.

Hyaluronidase will only dissolve hyaluronic acid fillers such as Restylane and Juvederm.  It will have no effect on silicone.