How Safe is Botox?

I've read that in lab studies, traces of Botox have been found in the brains of people who went through the procedure. Is this true, and is Botox really safe? The last time I got it, I felt very nauseous.

Doctor Answers 14

Botox is safe

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The FDA has a very rigorous process to determine the safety of products. The use of Botox to treat glabellar, between the eyebrow, wrinkles is very safe and approved by the FDA. The use of Botox to treat other areas such as around the eyes, the forehead and even around the mouth has been proven to be a very safe and effective means to treat facial wrinkles. So go ahead and enjoy the benefits of Botox Cosmetic.

Complications from Botox

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As with any medication there can be side effects. These side affects will vary depending on the dose, site and the experience and training of the person injecting the Botox. A complication might be some mild pain or tenderness or slight bruising. It is important to seek an injector with the right training and expertise to assure that the correct dose of Botox is injected and that the Botox is injected into the correct muscle.

Botox is very safe

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Botox is a FDA and Health Canada approved drug.  It is very safe.  It has been used for over 20 years for a variety of medical conditions.  It is the most researched drug on the market with a very long safety profile.  There are very little side affects to this drug.

David A. F. Ellis, MD
Toronto Facial Plastic Surgeon

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Botulinum toxin safety

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Botulinum toxin was first isolated in the 20s, was first used therapeutically in 1968, and became approved in 1989 for eye issues. It has been used heavily for cosmetic use since 2002, and it was the first aesthetic drug ever approved.  All that is to has a lot of safety data behind it. Recent evidence (coming out this week) proves that botulinum toxin does NOT enter your brain as it's distant cousin tetanus toxin does, which is where that theory came from. 

Botox, Dysport and Xeomin are the 3 botulinum toxins approved for cosmetic use in the US. They all work in the same way, at the presynaptic terminal blocking the release of acetylcholine - making the nerve temporarily unable to communicate with the muscle. It is broken down as a protein in our body with liver metabolism. Effects are temporary, and repeated use serves to take tension off of your skin, relaxing lines and wrinkles.

To ensure you are receiving the highest level of care, seek out a modernly trained, new-school dermatologic surgeon, oculoplastic surgeon, facial plastic surgeon or plastic surgeon who is board certified and fellowship trained in one of these "core four" cosmetic specialties. Membership in organizations like the American Academy of Facial Plastic and Reconstructive Surgery help to identify a highly trained surgeon.

Cameron Chesnut

#realself500 Physician

Botox Safety

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Botox is very safe.  The FDA has very tough standards to approve medications.  The Botox reminas within the treated area and should not migrate to other body areas.

Botox is powerful but safe

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Botox is a very powerful but safe medication. It is a very weak and dilute version of botulinum toxin. When Botox is administered directly under the skin or on the surface of muscle it will diffuse approximately 3 cm. 

Is Botox Safe?

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Hi Gale,

We think the study you reference is related to animals and not humans. The injection sites and doses for this study are different than for the Botox you would receive. Botox has been studied and used extensively for years and has a safer profile than the common aspirin.

Periodically we have patients feel light headed and nauseous during and after injections. While we have not determined if this is related to anxiety, pain or some other issue, we do recognize that it occurs sometimes. Patients recover from this fairly quickly after resting for a few minutes.

Harold J. Kaplan, MD
Los Angeles Facial Plastic Surgeon
4.4 out of 5 stars 7 reviews

Botox is safe and effective when used properly

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Botox has been used and studied extensively for a number of conditions from wrinkles to excessive sweating under the arms. The lab studies you are referrring to have been performed in rats and are not equivalent to the doses or sites used for humans.

Botox has a safe and effective track record. As always, research the individual who will be administering the Botox as well as their experiencing using this product.

Botox is very safe

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I think you’re referring to an animal study and not humans. Botox is very safe as it has been used for more than 30 years at high doses for neurology patients, much higher than that used for cosmetic purposes.

It is possible that if some Botox got in to a blood vessel that you might feel nauseated, or it is the technique of pain management during the delivery of the product that can cause this.

Ronald Shelton, MD
Manhattan Dermatologic Surgeon
4.9 out of 5 stars 38 reviews

Botox is among the safest of cosmetic procedures.

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To Gale,

Hi! Botox has been in use for a number of years with an excellent safety track record. When it is used for medical indications (as opposed to cosmetic), much higher doses are used, and it is safe even then.

The worst thing that's likely to happen from Botox is a local and temporary problem, such as a droopy eyelid, and even this is very rare with an experienced injector.

George J. Beraka, MD (retired)
Manhattan Plastic Surgeon

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.