The amount of discomfort during Fraxel treatment varies depending on the type of Fraxel and from patient to patient. The Fraxel re:store is not very painful but can feel like a stinging, prickling or burning senstion--similar to a sunburn. All patients have a numbing cream applied for one hour before the procedure, and for many of them that is all they need to be comfortable. However, if you are having a stronger treatment, if you are very nervous or if you have a low pain threshold you may want to take an oral medication such as Valium or Xanax or Vicodin. In that case, you should have someone with you to accompany you home. The Fraxel re:pair is a more aggressive treatment and is more uncomfortable. Usually, a combination of numbing cream, local anesthesia, and oral or light intravenous sedation is used for the Fraxel re:pair. The perception of pain is very different from person to person, so you should talk to your physician before your treatment so you know what to expect and have a plan.