Can I use Tretnoin after snail mucin & a layer of moisturizer? Will this affect efficacy?

Tretinoin is typically recommended to be applied directly onto clean, dry skin for maximum efficacy. This is because the active ingredient needs to penetrate the skin to work effectively, and applying it over other products could potentially reduce its absorption and effectiveness.
However, for some people with sensitive skin, applying tretinoin over a moisturizer (also known as buffering) can help reduce potential irritation. Snail mucin, which is known for its hydrating and healing properties, could potentially serve a similar function, although this is less commonly discussed in dermatological literature.
If you choose to use tretinoin after applying snail mucin and a moisturizer, it's important to let those products fully absorb into your skin before applying the tretinoin. This usually means waiting for about 20-30 minutes.
Remember, everyone's skin is unique, and what works for one person may not work for another. It is always a good idea to discuss your skincare routine with a healthcare provider or a dermatologist to ensure it's appropriate for your skin type and concerns.