Easy answer is use very temporary fillers (Restylane, Juvederm) first. There are simple to inject, last 3 months, are inexpensive. If after a trail with the temporary fillers you can proceed to a semi lasting filler (Perlane, ArteFill). Dermabrasion is a surgery that has healing time of 2 weeks to months, and is much more expensive. The basic physiology of upper lip wrinkling: 1. Loss of volume in dermis or a thinning of the tissue causing a valley/crater appearance; 2. muscle hyperactivity; 3. a combination. So the treatment is either fill the valley with a filler or fat vs sanding down the hills of skin on each side of the valley (vertical lines) in the lip. Hope this helps.