First, congratulations on your tremendous weight loss. That is an extraordinary accomplishment and something to be very proud of. It is common after significant weight loss to notice areas of facial hollowing, particularly around the mouth, cheeks, and temples. This can be accentuated if you are on medications such as GLP-1 inhibitors, since they accelerate fat loss in the face. Although some of these changes overlap with the natural aging process, they can appear earlier or more pronounced after such a significant transformation. Yes, the hollow area near your lip can often be improved. The most straightforward approach would be soft tissue augmentation. This can be done with either a dermal filler or with fat transfer. Hyaluronic acid fillers are the most common first step because they are precise, reversible, and provide an immediate result. Fat transfer is another excellent option, using your own fat to restore volume. Fat can provide a more natural and potentially longer-lasting correction, but the outcome is somewhat less predictable, and a portion of the transferred fat may resorb over time. Surgery is generally reserved for more advanced cases of facial aging or laxity. Given your age healthy skin elasticity, starting with either filler or fat transfer would be a very reasonable and conservative way to address this hollowing. It is important to do it carefully and conservatively, as even small amounts of volume can make a noticeable difference in the delicate perioral region. A consultation with a board-certified plastic surgeon will allow you to review the options in detail and decide whether a temporary filler or fat transfer best aligns with your goals. Sincerely,Michael Chung, MDPlastic and Reconstructive Surgery