White hyperpigmentation after a CO2 laser treatment is a rare but possible side effect. It occurs when the laser damages the melanocytes (pigment-producing cells) in the skin, resulting in a loss of pigment. While there is no guaranteed topical treatment that will fully restore the pigment to its normal color, there are some options you can explore. First and foremost, it's important to consult with a dermatologist who can evaluate the extent of the damage and recommend a personalized treatment plan. Depending on the severity of the hyperpigmentation, your physician may recommend a combination of treatments, including topical creams, chemical peels, or other laser treatments. Topical treatments such as hydroquinone, kojic acid, azelaic acid, and retinoids have been shown to be effective in treating hyperpigmentation. These treatments work by inhibiting melanin production and increasing skin cell turnover, which can help reduce the appearance of hyperpigmentation over time. It's important to note that these topical treatments can take several months to show results, and may not be effective for severe cases of hyperpigmentation. Additionally, some topical treatments can cause skin irritation or sensitivity, so it's important to use them under the guidance of a dermatologist. In some cases, a combination of treatments such as microneedling or PRP (platelet-rich plasma) therapy may also be recommended to help stimulate the production of new collagen and elastin in the skin, which can help improve its overall appearance and texture. In conclusion, there are several options available to treat white hyperpigmentation after a CO2 laser treatment. However, it's important to work with a dermatologist to develop a personalized treatment plan that takes into account your individual skin type and the severity of your hyperpigmentation.