Is it OK to have Botox treatment two days after having Polynucleotides treatment?

Question

Male, Caucasian, age 41

Anna Chacon, MD, FAAD · Answer

Thank you for your question. In general, it is considered safe to receive Botox two days after a polynucleotide treatment. Polynucleotides work by improving skin quality and stimulating tissue repair, while Botox functions by relaxing targeted muscles. Since they act through different mechanisms and in different layers of the skin, they do not interfere with each other’s effects.

That said, it is often recommended to allow at least several days between treatments to minimize potential irritation, swelling, or bruising in the treated areas. If both procedures are performed in close succession, it’s important to monitor the skin carefully and ensure the initial healing response from the polynucleotides has stabilized.

Stefan Weiss, MD · Answer

Polynucleotides are a new concept of regenerative medicine, which promote cell turnover, improve skin elasticity and hydration, heal sun damaged skin. As such, I would treat them like filler and do it AFTER a Botox treatment.

Laura Barriault, MD · Answer

Hello,As a general rule (and to keep it simple), always space out any beauty treatments (Facials, Botox/filler, PRP) by at least 1 week (7 days).
If you are having 2 treatments in a short amount of time, it is always better to ask the provider that will be giving each treatment about how to space it out in relation to the other treatment.
However, as a general rule, it is better to assume to space out any treatments by a minimum of 1 week (unless told otherwise by your provider). Some specific treatments need to be spaced out by 6+ weeks.

Is it OK to have Botox treatment two days after having Polynucleotides treatment?

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