Hi jaharned, thanks for your question. The good news is that CoolSculpting will not increase the likelihood of blood clots. And, taking aspirin is also fine, although you may have a higher instance of bruising. In addition, it is recommended that patients who require pain relievers post treatment take something that is not anti-inflammatory, such as aspirin or Tylenol as opposed to Ibuprofin. You will want to have consultation with a reputable CoolSculpting provider to make sure that you are actually a candidate. If you are, you will find that this is a very effective treatment that provides smooth, natural looking and permanent results. Good luck with your CoolSculpting journey!