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I mostly agree with Dr. Prendiville. It is not true that no studies have ever been done on botulinum toxin and pregnancy. It is true that there have been no randomized studies to establish the safety of botulinum toxin. It is unlikely we will have a formal answer. However, there are enough medical reasons why people get botulinum toxin that treating physicians do occasionally decide with their patient that for medical reasons the benefit of having botulinum toxin outweigh the risk to the fetus. There is a study that looked at a number of women in this situation and there were no apparent consequences of these treatments. For cosmetic indications, the medical community seems to agree that there is not enough safety information or reason to perform cosmetic botulinum toxin treatments on pregnant women. How about the situation where you got a botulinum toxin treatment at about the time of conception? Again we do not have a whole lot of information on this situation to state that it is safe. On there other hand we have no evidence that it is directly harmful either. I do not think you should loose sleep over this. However, if this does not reassure you, consider asking your obstetrician for a referral to a perinatologist for a consultation regarding your concerns.
Fist of all, congratulations. The next thing to do is discuss this with your Obstetrician. Although there shouldn't be any problems (Dysport is locally acting), no studies on Dysport have ever been or will ever be conducted on pregnant women. Therefore, neither Botox nor Dysport are administered during pregnancy, and all female patients of child bearing age receiving neurotoxins in my practice are asked about the possibility of pregnancy.
The bottom line is that we believe there are no effects on a developing fetus, but we will never test it, so we just don't know for 100% certainty. Dysport is a localized treatment and it affects the area it's put into. Additionally, only small amounts are used for cosmetic purposes. I would suggest you enjoy your pregnancy and not fret. You are not the first person this has happened to, nor will you be the last. "This answer has been solicited without seeing this patient and cannot be held as true medical advice, but only opinion. Seek in-person treatment with a trained medical professional for appropriate care."
