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Since Cosmelan contains hydroquinone at a higher percentage , using it for a prolonged time or using it repeatedly can lead to a condition called ochronosis. If Cosmelan is used as suggested by the manufacturer it should decrease hyperpigmentation and not increase it, and is completely safe.
Melasma is a common disorder that is oftendifficult to treat. It isn't unusual for a patient to become frustratedafter trying a variety of treatments in an attempt to obtainsatisfactory results. Like most other complicated skin conditions, acombination of treatments paired with the proper skin regimen works best!Topical de-pigmenting agents such as hydroquinone or other melanininhibitors along with a topical tretinoic acid to increase skin cell turnover, hastens the fading of uneven patches. This commitment along withspecific medical-grade chemical peels, appropriate laser treatments anddiligent protection , can enhance the likelihood of reducing or resolvingmelasma !#melasma #chemicalpeels # unevenskincolor
I have not had any patients whose melasma got worse after using Cosmelan, assuming they follow directions and use the system properly. I have had a few patients with tremendously stubborn melasma who we had to do the series on more than once, or once and then again a few years later. The key with maintenance though is to make certain that you wear a good sunscreen every day! "This answer has been solicited without seeing this patient and cannot be held as true medical advice, but only opinion. Seek in-person treatment with a trained medical professional for appropriate care."
Treating PIH and melasma with cosmelan may make your skin hypersensitive. I would suggest Melarase creams and Elevase Moisture Booster as part of the post-treatment regimen to reduce redness and pigmentation risk. Best, Dr. Karamanoukian Realself100 Surgeon
Our office specializes in hyperpigmentation problems. We currently employ the Melarase cream system which includes Melarase AM and Melarase PM used twice daily. Raffy Karamanoukian MD FACS