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Since Cosmelan contains hydroquinone at a higher percentage , using it for a prolonged time or using it repeatedly can lead to a condition called ochronosis. If Cosmelan is used as suggested by the manufacturer it should decrease hyperpigmentation and not increase it, and is completely safe.
Melasma is a common disorder that is oftendifficult to treat. It isn't unusual for a patient to become frustratedafter trying a variety of treatments in an attempt to obtainsatisfactory results. Like most other complicated skin conditions, acombination of treatments paired with the proper skin regimen works best!Topical de-pigmenting agents such as hydroquinone or other melanininhibitors along with a topical tretinoic acid to increase skin cell turnover, hastens the fading of uneven patches. This commitment along withspecific medical-grade chemical peels, appropriate laser treatments anddiligent protection , can enhance the likelihood of reducing or resolvingmelasma !#melasma #chemicalpeels # unevenskincolor
I have not had any patients whose melasma got worse after using Cosmelan, assuming they follow directions and use the system properly. I have had a few patients with tremendously stubborn melasma who we had to do the series on more than once, or once and then again a few years later. The key with maintenance though is to make certain that you wear a good sunscreen every day! "This answer has been solicited without seeing this patient and cannot be held as true medical advice, but only opinion. Seek in-person treatment with a trained medical professional for appropriate care."