Which drugs should take to reduce breast size and female symptoms?

Breast size might decrease with weight loss. Outside of that there is nothing that will reduce breast size when taken orally.

Typically medications are not used to reduce breast size.  You may want to discuss the symptoms you are having with your OB/GYN or primary care physician. Best wishes.

I do not know of a drug that you can take to decrease your breast size that would be safe. If your breasts are too large and you have symptoms from them, you might be a candidate for a breast reduction.