Dear Rosie, Thank you for posting your interesting question. If you want fillers to create high cheek bone definition, I would suggest fillers that are considered high G' fillers that lift the cheeks like Radiesse, Restylane Lyft and Voluma. Radiesse is a calcium based filler and Restylane Lyft and Voluma are considered hyaluronic acids. Botox is not a filler. Botox is a neurotoxin liquid that is usually injected to smooth facial wrinkles and does not provide any filling at all. For example, Botox is injected between the eyebrows to relax the so called 11's that form and make somone look angry. I recommend that you have a consultation with a Board Certified Plastic Surgeon, experienced with fillers, who can listen to your goals, examine you, answer all of your questions and make the appropriate recommendations to give you the high cheek bones and facial definition that you desire. Best wishes, Dr. Richard Swift