How Will DDD or E Cup Look Like After Breast Reduction to C Cup?

It may not be possible to go all the way down to a C cup if you are a DDD or an E cup now.   There are limitations based on the amount of tissue that must be preserved to maintain circulation and sensation to the nipple, and allow for healing of the skin.  It is best under these circumstances to tell your board certified plastic surgeon that you would like to get as close to a C cup as possible, and let them reshape your breast at the time of surgery to the size that is most appropriate based on your anatomy.  Then you will get the best breast shape that can be achieved, and maximize the chances of a risk free recovery!

Undergoing a breast reduction may provide significant benefits, including relief from physical discomfort caused by the weight of large breasts, such as back, neck, and shoulder pain. It can also enhance your confidence and make clothing fit better, offering a more balanced and proportionate look to your body. However, it's important to understand that while you may desire a specific cup size, predicting an exact cup size after surgery is not always guaranteed. Cup sizes can vary between different bra brands and styles, and factors such as breast shape, band size, and overall body proportions also influence how your breasts will look after the reduction. Surgeons typically focus on achieving a more aesthetically pleasing and proportionate shape, rather than targeting a specific cup size.
The goal of breast reduction surgery is to remove excess tissue, reduce breast size, and lift the breasts to improve their shape. The areola will also reduce in size and be more appropriately positioned on the breast mound. It is important to have a conversation about relative size with your surgeon during your consultation. While many patients experience a reduction in breast size of about 50% from their pre-surgery volume, the result will depend on your individual anatomy and the surgeon’s approach. I typically use the 50% as a reference to see if this is “too big, too small, or just right” for the patient’s expectations.
Your surgeon will discuss the desired outcome, considering factors like your body type and goals, but cup size alone shouldn't be the primary focus. The focus should be on achieving a comfortable, natural, and well-proportioned breast shape that enhances your overall appearance and alleviates discomfort.
Krishna Vyas, MD, PhD, MHSHarvard, Hopkins, & Mayo Clinic Trained Aesthetic Plastic SurgeonNew York, New York

It may seem appealing to choose what your new cup size would be, but that's actually not how the surgery works. While it is very helpful to know what a person’s goal breast size might be, it is not possible to choose an exact cup size before surgery. Every bra from each company sizes their cups differently, and the cups also vary based on a person’s overall body size. The best approach is to provide your Doctor with a photo of your ideal breasts on someone who has a body similar to your own. She can then focus on shape, not size, and discuss a realistic outcome with you for what you're looking to achieve.
However, going from such a large size to a smaller size for yourself, would make a significant difference. You would have reduced neck and back pain, a more proportional look, increased confidence and self-esteem and a more youthful appearance. With smaller breasts also, women enjoy that their breasts are less droopy and their shape is much improved. So there are not only functional benefits but also aesthetic benefits from breast reduction surgery.