Botox is one of the most commonly prescribed pharmaceuticals in the world and YES, it may be used (off label) to minimize lines at the mouth. It's good that you are investigating options on Real Self, but I strongly urge to schedule personal consultation at a board-certified plastic surgery practice to really understand your options and get the result you want. As an example, Voluma (in the Juvéderm family of products) is recently FDA approved. This dermal filler is especially for cheeks. You may find that plumping up your cheeks with Voluma injections may raise your droopy mouth and - dare I say it? - put a smile on your face.My point simply is do your homework and consult with an expert to find the right solution for you. Good luck to you!
Botox can be helpful in lifting the corners of the mouth for a patient who has a stronger contraction of the muscle that pulls the corners down, called the depressor anguli oris. I have found that most of the time filler is much more beneficial in lifting the corners of the mouth than Botox alone. The combination of Botox and filler can give the best result in many patients. The best treatment will depend on the reason for your "droopy" corners of the mouth. Please consult a board certified physician experienced in Botox and filler of the lower face to evaluate the best treatment plan for you. Best wishes.