Does Botox Have to Be Diluted Before Injecting?

Botox is shipped as a powder. Sterile saline is added to the bottle, with the amount of volume added determining the dilution. There is an acceptable range, and there are benefits and drawbacks to each endpoint.

With higher concentrations it may be a little harder to control the dose, but there is less diffusion. Lower concentrations make it easy to measure dosages; however, the more dilute botox spreads farther. This is bad when nearby muscles are inadvertantly paralysed, but can be good for treating larger areas like the central or upper forehead.

Yes, the product must be diluted during the reconstitution process according to current protocols since it arrives with a freeze dried powder in the vial.