Is the mixture (tretinoin 0.1% & azelaic acid 20%) effective in treating melasma?

I would suggest the Melarase creams including Melarase AM and Melarase PM for lightening the face in the setting of melasma. Fractional lasers can further lighten. Best, Dr. KaramanoukianLos Angeles

Melasma needs a combination approach to get the best improvement and will need a series of treatments. In our practice, we combine Clear + brilliant, peels, microneedling/PRP, aerolase, and sometimes erbium laser (coollaser) to get the best results. See an expert for a formal evaluation. Best, Dr. Emer

This is a mild formula but I would combine this with Melarase cream or the Brightening Kit. BestH Karamanoukian MD FACS

Absolutely, it can help, but the use of other methods including SPF++ and lasers can help even more, not to forget HQ and tablets. Video explains everything in detail. Dr Davin Lim. Brisbane. Australia.