Thank you for your question. You’re asking about the efficacy of PRP as you haven’t seen much about PRP in popular hair loss forums. You have concerns about the shedding and possible shock loss related to PRP, so you’re looking for some independent information, and if it’s just an expensive placebo. I can give you some guidance on this which I deal with everyday in our practice. A little background: I’m a Board-certified cosmetic surgeon and Fellowship-trained oculofacial plastic and reconstructive surgeon. I’m the founder of TrichoStem® Hair Regeneration Centers, a system we developed using PRP and extracellular matrix for non-surgical treatment of male and female pattern hair loss. I’ve been in practice in Manhattan and Long Island for over 20 years, and I have been taking care of hair loss patients for this time, and I have extensive experience with hair transplant surgery. I’ll start by clarifying agendas a little. When you asked about the independent study of PRP, you have to also understand that in medical studies in general, there always has to be a source of funding. Very often there is an agenda with a lot of medical studies, particularly when it benefits the sponsoring company or entity. For example, if Allergan, and not isolating Allergan, wants to show the benefit of a particular injectable filler, they will sponsor a study. The study may be for FDA approval, but for other reasons as well. The same thing goes for universities or anywhere medical studies are performed. When it comes to something like PRP, one of the struggles is no large entity gains from people using PRP. The only people who really make money on PRP from the industry point of view are the people who make the kits, and they're not as capitalized as much larger entities. When you don't hear about PRP, or have a lot of conflicting information about it, part of it is due to this issue. As a cosmetic surgeon, I can tell you that PRP does have incredible efficacy in a lot of areas: we use it every day in our practice for acne scars, pigmentation, wrinkling, damaged skin, and for wound healing. When it comes to hair loss, the prevailing opinion of my colleagues who use PRP is it does help hair loss, but in my experience PRP alone does not have long-term benefit for hair loss. From our experience, PRP stimulates short-term growth of hair, kind of like a boost. If there's hair that is not growing, you get a PRP injection and will get some growth, but it won't sustain - it will stop growing. People come to who have had PRP injection done elsewhere often report they got PRP done monthly, and unfortunately a lot of people have experienced discomfort getting these PRP injections. After about the fourth month of getting these injections, and felt their scalp was being hurt, and they weren’t seeing endpoint of getting these injections. In our practice we developed a treatment called Hair Regeneration where we’ve learned how to combine PRP with a material called extracellular matrix which was originally intended for wound healing. Long story short, when using these materials for healing of grafts and the donor area after a hair transplant, the side effect was thinning hair became thicker. The tricky part was figuring out how to dose it, deliver it, and customize it, so it took several years to develop the system we call TrichoStem® Hair Regeneration. We treat people from all over the world for both male and female pattern hair loss. This treatment uses PRP, but not PRP alone. We’re able to stop the progression of hair loss, restore the growth cycle so thinning hairs grow in thicker, and reactivate hair that's not growing. From one treatment session, we have patients who have continued to grow hair effectively for more than 5 years. This is not a monthly treatment - it was one treatment over 5 years ago. We follow our patients very closely, so we see patients who live within the tri-state area every 3 months, then beyond that we see people yearly. For people who travel from outside of the country, we encourage them to come as often as possible, and customize to individual needs. If you are trying to understand the benefit of PRP, you have to make a distinction between PRP alone, PRP in conjunction with hair transplant, or PRP the way we use it in Hair Regeneration. It common practice for people to do extensive research, but I think it's also important to go out and meet with doctors personally. Interacting only online can only get you so much information. When you meet a doctor who has experience and is actually in the frontline, it’s a very big distinction between the academic world and the clinical world. We treat patients from all over the world - we’re in the frontlines helping people and seeing patients every 3 months, so this treatment has to be successful, otherwise we would stop doing it. You can look for many studies, but when you meet doctors who have real success with real patients who they treat daily, you can't get better than that. Learn more, meet with the doctors, and hopefully you'll find a find a solution that works for you. I hope that was helpful, I wish you the best of luck, and thank you for your question