Latisse eye colour change? I have hazel eyes. A way to reduce risk to 0?

Hello Julia,You are correct in understanding that hazel eyes have a higher risk but given the small concentration of the bimatoprost (the medication making your lashes grow) and the topical application, there are no reports of people experiencing eye color change.  When directly applied in the eye to help as a glaucoma medication, there were only a handful of incidences where the spots in hazel eyes darkened.  With that being said, there is still a very minute risk that it could happen and there are always alternatives that involve growth factors like Omni Lash and Brow Growth Complex.  Help this helps.All the best,Carlos Mata, MD, MBA, FACSBoard-Certified Plastic Surgeon

Hello,Thank you for your question. While there is a risk of that happening, it is extremely rare. It was mainly caused when a similar medication was used as an eye drop and dropped into the eye on a regular bases. You may want to consider using a thin eye liner brush to apply the Latisse to the eye lid. Good luck!

When applied as directed to the top of the lids, Latisse should not affect the color of the eye. Keep in mind, no patients in any of Allergan’s studies for Latisse reported alterations in their eye color, so this would be an extremely rare side effect. Prp and viviscal can also help improve eyelash growth. Best, Dr. Emer

The risk of pigmentation will never be zero, but I can give you a little more information about the Latisse studies. 
Read the study from 2010 by Law, S called "Bimatoprost in the treatmet of eyelash hypotrichosis."  Here is what they wrote -- increased iris pigmentation has been cited as a side effect of ophthalmic bimatoprost when used in glaucoma treatment. However, iris pigmentation changes were not noted in the clinical trial of bimatoprost used for promoting eyelash growth. This is probably because the drug was applied at the lid margin and the root of the eyelashes and intraocular penetration was therefore minimized. Since iris pigmentation change, associated with use of ophthalmic prostaglandin analog, can be permanent, patients who desire to use bimatoprost to promote eyelash growth must be informed of this possible side effect.
This is just one of many studies done on Latisse as an eyelash treatment, but should give you at least a little bit of relief around the risk of pigmentation.

As with all medications, there are none that is zero risk. Although the risk of eye colour change is rare, it is possible. Proper Latisse application minimizes this risk. All the best. 

There is no way to make the risk zero. Proper application makes any such risk low but never zero. The eyelid is a thin membrane and the eye is a wet surface. Studies have not shown risk with topical application.

Hello Juliahansen88,  Latisse has been a product I've sold in my practice for years.  Many patients with light colored eyes (including my staff), have used this product with no color change at all.  I have been reassured many times by the company's representative that there is no risk in eye color change by applying it to the upper lid with the applicator as directed.  When using the appropriate company directions there should be no issue.  I would have no apprehension placing any of my patients on it. 
All the best,
Dr. Mahajan

I have sold thousands of kits of Latisse. No one has had their hazel eyes change color. My daughter has hazel eyes and thought she was putting her eyedrops in, and actually put a full drop of Latisse in her eye. They are fine. Her eye color did not change. It requires repeat application directly into the eye to change them - like when you use a similar product for glaucoma, not for eyelash growth. If you close your eyes and use the proper application, your hazel eyes will remain hazel. "This answer has been solicited without seeing this patient and cannot be held as true medical advice, but only opinion. Seek in-person treatment with a trained medical professional for appropriate care."