Does Biofilm Preclude PRP treatment?

Question

I've had a confirmed biofilm in my face due to dermal filler. Unfortunately, it left me with a great deal of volume loss and a huge line under my tear trough. Does the biofilm preclude PRP treatment? Trying to figure out how to fill in hollows safely without recurrence, spread of infection. Thanks.

Patrick Yam, MD · Answer

If the PRP is formulated properly, it can help with biofilm and associated microbial colonization. Several studies (Gilbertie 2020, Pall 2023, Schuldt 2021), have shown that PRP has anti-microbial and antibiofilm properties. The PRP should be high concentration, e.g. a platelet concentraiton of at least 1 million/µL and low in leucocytes and red blood cell contamination. The only way to ensure high concentration, dose and proper composition is through PRP testing and analysis of each treatment. PRF would have a similar benefit. Over time, such treatments could help with the biofilm and with volume loss through tissue regeneration.

Does Biofilm Preclude PRP treatment?

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Does Biofilm Preclude PRP treatment?

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Everything you need to know about PRP Injections

Our mission is to create a world where every investment in modern beauty is Worth It.