Does Accutane make period cramps worse?

Thank you for your question.Any possible side effects or new symptoms after starting a medication should be brought to the attention of the prescribing physician. Isotretinoin could be the culprit of your symptoms, but can also be a sign of something else going on in the body. I highly recommend you consult with your prescribing dermatologist and consult with your OBGYN regarding the menstrual cramping. Take care and good luck.