Hello, Thank you for your question. Accutane (isotretinoin) is a potent medication often used to treat severe acne. It works by significantly reducing the amount of oil released by your skin's oil glands and is known for its effectiveness. However, it also has a range of side effects, including making the skin more sensitive and prone to irritation. Regarding the use of diode laser treatments while on Accutane, traditionally, it has been recommended to avoid laser treatments, including diode lasers, during and for several months after completing an Accutane course. The primary concern is that Accutane can increase the risk of skin complications such as scarring, delayed wound healing, and skin irritation when combined with laser treatments. While some studies might suggest that there are no significant problems with combining these treatments, it is crucial to proceed with caution. The skin's healing response can be unpredictable while on Accutane, and any invasive procedure, including laser treatments, could potentially lead to adverse effects. I recommend discussing your specific case with your dermatologist. They can assess your skin condition and treatment plan to provide personalized advice. They may suggest postponing diode laser treatments until after you have completed your course of Accutane and your skin has had time to recover.