I've Been on Accutane for 5 Days and my Face is Burning - Is That Normal?

Doctors often refer to the dryness that occurs with isotretinoin and retinoids like Retin-A as the retinoid reaction. Although normal, the dryness can lead to a feeling of discomfort that can ultimately compromise your compliance. Retinoid reaction includes:
DrynessRednessItchingBurningDiscomfortIn my office in Beverly Hills, I prescribe Accutane quite a bit for cystic acne and inflammatory scarring. Patients are advised to moisturize frequently with a non-oily moisturizer such as Elevase Moisture Booster, which we use in our office. Applied liberally on the face, the ceramides are soothing and relieve discomfort when possible. 
Best, 
Dr. Karamanoukian
Realself100 Surgeon

This is very odd. I would make sure that you are not getting any sunlight on your face without adequate sunscreen. I would use a moisturizer to replenish your skin lipids and take oral vitamin E to reduce some dryness. Make sure your multi vitamin does not have vitamin A in it which can add to Accutane dryness.