Hi, that’s a very thoughtful question, I appreciate you thinking about how treatments might interact with one another. In general, having a CryoPen treatment on the scalp should not interfere with the collagen stimulation from Radiesse in your jawline. These treatments work locally in the areas where they are applied. CryoPen uses controlled cryotherapy to treat superficial skin lesions by freezing targeted tissue. Its effects are confined to the specific area treated — in your case, the scalp. Meanwhile, Radiesse works deeper in the tissue of the jawline by stimulating collagen production through calcium hydroxylapatite microspheres. The collagen response is localized to the injected area. Because they are in completely different anatomical regions, there’s no meaningful biological overlap that would reduce collagen production from Radiesse. The only time we become cautious is if multiple energy-based or inflammatory treatments are done directly over or very close to recently placed filler. But a scalp cryotherapy session and jawline Radiesse are independent of each other. It’s completely understandable to want to protect your investment in collagen stimulation. Fortunately, these two treatments should not interfere with one another.