Sculptra does work to restore collagen. It is important to take certain factors into account with patient selection like age, skin quality, and degree of volume loss. These factors will affect the number of vials you will need and how your body responds. Facial fat loss, or lipoatrophy, is the loss of fat beneath the skin which occurs with the normal aging process, after weight loss, or due to a medical condition. This can result in sunken cheeks, indentations, and hollow eyes and temples, leaving you with excess sagging skin especially around the mouth. Sculptra works by filling in hollow areas and by stimulating the body to produce collagen and underlying tissue for a long-lasting, fuller, natural, and more youthful look. By filling out the deflated skin, the sagging face appears tighter. Sculptra is composed of the same substance used in dissolvable stitches and various soft tissue implants.