I have Retin-A and Meladerm. I would like to use them for hyperpigmentation/melasma. Can you use both?

Question

Right now I'm using a pea size amount of retin a every other night. Could I apply meladerm in a.m. And the nights I use retin a, use a pea size amount of retin a and meladerm together?

Raffy Karamanoukian, MD, FACS · Answer

Melasma is associated with hyperpigmentation caused by a combination of hormones, sun exposure, inflammation, and deposition of melanin pigment. In our office, we specialize in melasma treatments and start with Melapads, Melarase AM, Melarase PM, and Replenish; followed by pulsed dye laser to eliminate inflammatory erythema and light fractional laser. 
  
Best, 
  
Dr. Karamanoukian
  
Realself100 Surgeon

Jeff Angobaldo, MD · Answer

Thank you for your question.   I would recommend to start using triluma morning and night six weeks prior to laser treatment. Fractional treatment is very effective for suppressing discoloration and evening out skintone.  Skinpen which is a microneedling device that would also be beneficial for getting rid of melasma.  The microneedling treatment helps to wake up your natural growth factors, shrink your pores, fade discoloration and acne scars, and help increase collagen and elastin production. You would do a treatment every 4 weeks and stay out of the sun as much as possible and always wear spf 50 broad sprectrum.  Always consult with your physician first before starting a treatment

Davin Lim, MBBS, FACD - Account Suspended · Answer

Yes you can however be careful of skin irritation. Titrate or use every other night, and slowly slowly build up. Retin A can cause skin irritation so take things slow. Best results are seen when lasers combined with topicals. Melasma can not be completely cured, however effective treatment are possible. This is because your skin is extremely sensitive to UV and even the smallest amount can stimulate your pigment cells to produce colour. The mainstay of treatment is strict UV protection- hats, sunglasses and SPF every 4 hours. 
  
I prefer to use a combination of creams and laser for melasma. Hydroquinone can be used (5-8%), along with vitamin A creams. I usually start my patients on laser (low dose Q switch or Picosure) a few weeks after they commence on creams. Another laser I use is the Clear and Brilliant in the Permea setting combined with creams. 
  
In some cases I combine glycolic AHA peels, and in other cases I use a tablet called Tranexamic acid to help. Melasma treatments should be tailored to each patient. 
  
All the best, Dr Davin Lim. Laser, surgical and aesthetic dermatologist. Brisbane, Australia

David E. Berman, MD (retired) · Answer

you will need 3 treatments, each spaced one month apart. the picosure laser is a breakthrough laser because it fires 1,000 faster than other lasers. This means there is no downtime and little to no redness. you will need to use a good sunblock.david berman md

I have Retin-A and Meladerm. I would like to use them for hyperpigmentation/melasma. Can you use both?

Answers (4)

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