Evolence is derived from a pig or porcine source, which is felt to have very, very low allergic potential. It is new and exciting because it has unique characteristics that separate it from other fillers available on the market. Studies in the United States show that Evolence has comparable longevity to the hyaluronic acid derivatives such as Restylane and Juvederm, lasting six months. However, studies in Europe have suggested that this filler may have longevity of up to 12 months. The reason this product lasts somewhat longer than the hyaluronic acid derivatives is felt to be secondary to its unique way of linking the strands of the collagen molecule together. It has a very unique patented technology called Glycomatrix™, which is responsible for the unique structural characteristics and longevity noted with this filler. Evolence also has excellent flow characteristics, which again give it a very smooth and natural appearance. Evolence also is well liked by consumers and physicians because it gives the face excellent structural integrity.
Evolence safety has been shown to be remarkable in multiple studies and requires no skin testing. A second generation filler called Evolence Breeze is now under investigation, which can be used for shaping and molding the lip naturally. Evolence is truly the re-birth of the collagen molecule.