Latisse and eye color.
Latisse, also called bimatoprost, is a drug that was originally used to treat glaucoma. In extremely rare instances patients had permanent darkening of their light colored eyes when applying the drug directly to the eyeball.
It is reasonable to assume there is an extremely small chance for this side effect, even though Latisse is applied directly to the eyelashes and not to the eyeball.
Darkening of the eyelid skin can occur, albeit infrequently, but resolves when...