Plasma Skin Regeneration (PSR) or Laser?

Stephen Prendiville, M.D. answers: Which laser treatment is best for facial rejuvenation and skin tightening?

I am planning on having skin resurfacing done. I am 45 with lax skin and a few acne scars, jowls. My goal is skin tightening (within reason), skin rejuvenation, and just overall healthier look.

I have been to 2 doctors- one said he would use the Active FX (this is his strongest laser) and the other suggested Fraxel repair (i have had 2 fraxel restore with some improvement).

Which of these two treatments is the most aggressive? What is the typical price point for them, if you know? Thanks , L


Stephen Prendiville, MD
14 months ago

Facial rejuvenation via skin resurfacing has been available in many forms over the years.  The original cosmetic treatments consisted of chemical peels (believed to have been used by the Ancient Egyptians) and dermabrasion.  These modalities work very well but are not without risk.

The next generation of resurfacing was achieved with abalative lasers, the earliest of which was the CO2, and later erbium modalities.  The extended downtimes of lasers and risk (most particularly CO2) has lead to a decline in usage, despite potentially great results.  Since then, newer fractionated and non-ablative lasers have also been introduced and ceratinly have both positive and negative features.

For the last two years in my practice, I have incorporated a newer, non-laser modality for facial rejuvenation and skin tightening known as Nitrogen Plasma Skin Regeneration (PSR), made by Rhytec.  The PSR can be used in both a low energy (PSR-1) or high energy treatment (PSR-3). 

The principle of how it works is based on excitation of Nitrogen gas, which forms an ionized form of Ntrogen known as plasma (similar to the principle in "Plasma" TV sets). The energy is then released on the skin, causing a controlled area of injury on the skin.  The skin is left on as a biological layer for 3-5 days, and then peels away.  An initial rejuvenative result is obtained, followed by further skin tightening over the course of the next year (caused by increased collagen deposition and remodelling). 

The benefit of the PSR is less redness, less downtime, less risk of scarring, and less risk of hypopigmentation than with conventional lasers such as the CO2.  A PSR will achieve 70-80% of the wrinkle reduction and skin tightening result of the CO2, depending on the skin type and the extent of skin damage.

Patients must consider the combination of results, downtime, and risks when assessing facial resurfacing. There are many modalities available, many of which work well.  Understanding the potential upsides and downsides is essential to being happy with the ultimate outcome.

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