Some medications are used off-label by board-certified dermatologists and plastic surgeons because if we all waited for the FDA to approve of treatments, then we would have very few safe options. For example compounding a topical steroid with an antibiotic to treat perioral dermatitis, and for many years dermatologists injected Botox into crow's feet wrinkles before it finally was FDA approved this year. One more example: For many years, dermatologists studied and offered injection of Botox into the armpits for sweating until it finally was FDA-approved. It is important that the off-label treatment be discussed and that it be consented to formally in the physicians consent form. There are many ways to rejuvenate and slenderize the chin, jowls, neck. Some experienced and skilled dermatologists and plastic surgeons do offer Botox treatments for the jawline and neck, and it is sometimes referred to as the Nefertiti Lift. Botox may also be injected lower in the platysma muscle on the neck to reduce wrinkles. However, Botox only lasts 3-4 mths.If you have residual fat under the chin or jowls, you may consider Lipodissolve. Another option, for saggy skin of the neck and chin, would be to have skin tightening with either Ulthera, Radiofrequency (Invasix, EMatrix) or with Gentle Yag Laser (Fotona 1064nm). Despite what the manufacterers might claim for these treatments being "one-time only" most of them, in my opinion, need multiple treatments. At our office we prefer the Gentle Yag because it is the least painful, the fastest, and least down-time.Anyway, good luck