Will Hyaluronidase Correct an Uneven Lip Augmentation Result?

Question

I have recently had half a syringe of Hydrafill with a bad result - the product has collected in the wrong part of the lip and it's uneven. If I was to use hyaluronidase to correct an uneven result I have had recently with Hydrafill, would it dissolve all product in the mouth or would you be able to inject a tiny amount into certain areas without it spreading? I have been having injections for 10 years and am happy with the size of my lips, so I'm worried it will completely dissolve the Hydrafill and I will have to start from scratch. Thanks for any help.

Harold J. Kaplan, MD · Answer

Hyaluronidase injections are a valuable option when hyaluronic acid fillers need to be dissolved.  You are correct in being concerned with whether or not the hyaluronidase can "spot treat" just the one area that appears over-filled.  There is no way to tightly control where the enzyme will work and no way to contain the effects.  However, we have found that using very small amounts of hyaluronidase, combined with patience, makes this a good treatment option for many without reversing the total effects of the original treatment.

Dmitriy Schwarzburg, MD · Answer

Hyaluronidase is designed to dissolve fillers made of hyaluronic acid. If you are not satisfied you can always have it dissolved. Please contact a qualified provider or a board-certified physician with extensive experience in these procedures.

Paul Watterson, MD · Answer

Hyaluronidase is a protein enzyme that degrades hyaluronic acid and is  what makes the use of fillers such as Juvederm, Voluma and Restylane so appealing.  These hyaluronic acid fillers can be reversed if we don't like them!  It works almost like an eraser and usually does so within 24 hours.  This gives these fillers a huge advantage over others which cannot be reversed so easily.  That said, it is so much better to add incrementally than subtract and have to start over.  Expense is another issue to consider.  Everyone who injects fillers should have hyaluronidase on site and ready to go should the need arise.

D.J. Verret, MD · Answer

Unfortunately, hyaluronidase will fix your problem but you will have to start from scratch. By its nature, hyaluronidase will dissolve into the surrounding tissues and dissolve any hyaluronic acid in its path.

Pat Pazmino, MD, FACS · Answer

Dermal fillers are an excellent option for lip augmentation. However, it is possible to develop an uneven result after an injection. Your best bet is to work with a board-certified plastic surgeon was a great deal of experience working with lip tissue and dermal fillers. They will be able to assess you and let you know if you would best be served by the addition of more filler into other areas to balance your result or a portion of the dermal filler may be drained, or if an injection of a small amount of hyaluronidase will correct this. Hyaluronidase is a powerful enzyme that can help break down a hyaluronic acid-based filler.

Will Hyaluronidase Correct an Uneven Lip Augmentation Result?

Answers (7)

Answer: Hyaluronidase is Non-Specific

Answer: Hyaluronidase is Non-Specific

Answer: Correcting an uneven lip augmentation with hyaluronidase

Answer: Correcting an uneven lip augmentation with hyaluronidase

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Everything you need to know about Hyaluronidase

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Will Hyaluronidase Correct an Uneven Lip Augmentation Result?

Answers (7)

Answer: Hyaluronidase is Non-Specific

Answer: Hyaluronidase is Non-Specific

Answer: Correcting an uneven lip augmentation with hyaluronidase

Answer: Correcting an uneven lip augmentation with hyaluronidase

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Recommended reading

Everything you need to know about Hyaluronidase

Our mission is to create a world where every investment in modern beauty is Worth It.