When Will I Notice the Results of the Botox?

Had botox between eyes, frown lines 2 days ago... I see no difference.

Doctor Answers 44

BOTOX Cosmetic takes time to work

In general, a patient should notice some effect of the BOTOX Cosmetic within 4-7 days of it being injected. However, this time may be shorter in some individuals. The complete effect is generally seen by 14 days after the date of the injection.

One of the most frequent misconceptions is that BOTOX Cosmetic will work immediately. It is important to understand how BOTOX Cosmetic works.

After BOTOX Cosmetic is injected into the muscle, it takes time for it to bind to the receptor responsible for sending the signal to release a chemical that results in muscle contraction. Until this binding takes place, the patient will not see an effect. This process takes a different amount of time in different people.

I recommend that all patients be seen two weeks after being injected with BOTOX Cosmetic. This will allow your physician to critically evaluate the results. If you are pleased, it will allow the physician to know this so he/she can repeat the injection technique in the future. If you are not completely satisfied, a dose adjustment ("touch up injection") can be performed to meet your expectations. This will also allow your physician to adjust his/her technique in the future.

Remember that BOTOX Cosmetic will not remove lines or wrinkles that are already etched into the skin. For this, one should consider skin resurfacing (e.g., chemical peels, laser, dermabrasion) and/or injectable filler materials (e.g., Restylane, Juvederm).

Be sure your physician has the proper training, credentials, and experience. Communicate your goals before your injection. This will allow your physician to meet and hopefully exceed your expectations.

Botox Effects can be seen 3 to 5 days after treatment: Botulinum Type A

Botox Cosmetic and Effect of Botox

Botox Cosmetic is produced by Allergan. Botox is a name brand for Botulinum Toxin Serotype A and is effective for the reduction of dynamic wrinkles in the forehead, eyebrow area, crow's feet, and perioral area.

Botox works by stopping the output of a specific neurotransmitter known as Acetylcholine across the nerve. Although the effects of Botox occur immediately to stop the release of Acetylcholine, there is still some reserve of the chemical that will last about three to five days in the nerve synapse. Once the reserve is used up, then botox will succesfully stop the release of further Acetylcholine for several months.

In my Santa Monica office, I instruct my patients to follow a strict exercise protocol after their injection.

Questions: spakare@yahoo.com

Raffy Karamanoukian, MD www.karemd.com Kare Plastic Surgery & Skin Health Clinic Santa Monica, Los Angeles Plastic Surgery

Raffy Karamanoukian, MD, FACS
Los Angeles Plastic Surgeon
4.8 out of 5 stars 90 reviews

You should notice the Botox starting to work in 2-3 days...

You should notice the Botox starting to work in 2-3 days. Over the course of 7-10 days, the effect will become stronger. In my practice, I ask patients to return at two weeks as that point they should be seeing maximal effect. As is mentioned in other forums, lines between the brows can be due to either muscle motion or tethering of the skin to deeper structures. This means that for maximal effect you may need Botox + some type of filler. More permanent options are available.

D.J. Verret, MD
Dallas Facial Plastic Surgeon
3.8 out of 5 stars 13 reviews

Botox - starts to work in a few days; complete results in 2 weeks

Botox typically starts working in 1-4 days.  Your muscles will weaken further, and you will have your final results in 2 weeks.  Touchups are generally done after 2 weeks have passed.


Most patients begin to notice a result within 2-3 days following injection.

Most patients begin to notice a result within 2-3 days following injection of Botox. Patients may require 7 days to notice their 'final' result. If you do not notice an effect or your desired result after 7 days, it is a good idea to see your physician who did your treatment. You may require additional units of Botox to see the desired effect.

Sanjay Grover, MD
Orange County Plastic Surgeon
4.9 out of 5 stars 177 reviews

Botox time to work

Botox typically takes 2-3 days to begin to work. The complete effect can take about a week. If after a week you haven't seen an improvement you should see your doctor.

Pre-injection and post-injection photos can be very helpful in documenting the improvement. Your doctor should also keep close records documenting how much they've injected, at what concentration and where.

Be sure to find a board certified plastic surgeon or dermatologist. At my practice, I perform all the injections personally.

I hope this helps.

Full results show within 2 weeks.

You may notice the results of Botox within 3-4 days; however, the full results can be seen in 2 weeks. Try to resist the urge to add more Botox until you wait out the first 2 weeks.

Ava Shamban, MD
Santa Monica Dermatologic Surgeon
3.9 out of 5 stars 9 reviews

Don’t worry, two days is too early to see any effect in most people.

Botox effects will generally start to be seen anywhere between 3 and 7 days following injection, with full effects appearing after two weeks. Don’t worry, two days is too early to see any effect in most people.

Botox generally begins to work within 3-7 days following injection.

Botox generally begins to work within 3-7 days following injection, with full results apparent at two weeks. Be patient, and you should begin to see results soon. If after two weeks you are still unhappy with the amount of correction, visit your injector again for a touch-up, as you may need a few more units.

Botox results

Botox will take affect in 7-10 days.  Sometimes a little sooner sometimes a little later.  

Good Luck

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.