In general, a patient should notice some effect of the BOTOX Cosmetic within 4-7 days of it being injected. However, this time may be shorter in some individuals. The complete effect is generally seen by 14 days after the date of the injection. One of the most frequent misconceptions is that BOTOX Cosmetic will work immediately. It is important to understand how BOTOX Cosmetic works. After BOTOX Cosmetic is injected into the muscle, it takes time for it to bind to the receptor responsible for sending the signal to release a chemical that results in muscle contraction. Until this binding takes place, the patient will not see an effect. This process takes a different amount of time in different people. I recommend that all patients be seen two weeks after being injected with BOTOX Cosmetic. This will allow your physician to critically evaluate the results. If you are pleased, it will allow the physician to know this so he/she can repeat the injection technique in the future. If you are not completely satisfied, a dose adjustment ("touch up injection") can be performed to meet your expectations. This will also allow your physician to adjust his/her technique in the future. Remember that BOTOX Cosmetic will not remove lines or wrinkles that are already etched into the skin. For this, one should consider skin resurfacing (e.g., chemical peels, laser, dermabrasion) and/or injectable filler materials (e.g., Restylane, Juvederm). Be sure your physician has the proper training, credentials, and experience. Communicate your goals before your injection. This will allow your physician to meet and hopefully exceed your expectations.